您好，欢迎来到化工原料网！ [登录] [免费注册]
化工原料网
发布求购
位置：首页 > 产品库 > (Rac)-3′-Hydroxy simvastatin
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
(Rac)-3′-Hydroxy simvastatin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(Rac)-3′-Hydroxy simvastatin图片
CAS NO:126313-98-2
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
(Rac)-3′-Hydroxysimvastatin是一种Simvastatin代谢物。Simvastatin是一种竞争性的HMG-CoA还原酶抑制剂，Ki值为0.2nM。
Cas No.126313-98-2
别名辛伐他汀杂质
Canonical SMILESCC(O)C(C)(C)C(OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(O3)=O)C12)=O
分子式C25H38O6
分子量434.57
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(Rac)-3′-Hydroxy simvastatin is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[1][2].

[1]. Slater, E.E., et al. Mechanism of action and biological profile of HMG CoA reductase inhibitors. A new therapeutic alternative. Drugs, 1988. 36 Suppl 3: p. 72-82.