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(E)-10-Hydroxynortriptyline
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(E)-10-Hydroxynortriptyline图片
CAS NO:47132-16-1
包装:5mg
市场价:4950元

产品介绍
(E)-10-Hydroxynortriptyline(E-10-OH-NT)是Nortriptyline的代谢物。Nortriptyline是三环类抗抑郁药，是Amitriptyline的主要活性代谢物，用于缓解抑郁症状。
Cas No.47132-16-1
别名E-10-OH-NT
Canonical SMILESOC1C2=CC=CC=C2/C(C3=CC=CC=C3C1)=C/CCNC
分子式C19H21NO
分子量279.38
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline . Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].

[1]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8. [2]. Shimoda K, et al. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology Information (US); 2012-2017 Mar 23.