CAS NO: | 68003-38-3 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Cas No. | 68003-38-3 |
别名 | 2-(4-氯-3-硝基苯基磺酰胺基)苯甲酸 |
化学名 | 2-((4-chloro-3-nitrophenyl)sulfonamido)benzoic acid |
分子式 | C13H9CIN2O6S |
分子量 | 356.74 |
溶解度 | DMSO:125 mg/mL(350.40 mM) |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | CTPI-2 (SLC25A1 inhibitor CTPI-2) is a novel specific SLC25A1 inhibitor with Kd of 3.5 uM, CTPI-2 is synthetic lethal with cisplatin or with EGFR inhibitor co-treatment and restores antitumor responses both in vitro and in vivo; disrupts self-renewal and sphere-forming capacity of the indicated tumor cells relative to monolayer cultures, demonstrates broad activity on lung CSCs, inhibiting mitochondrial respiratory activity, self-renewal and matrix invasion; inhibits tumor growth in in vivo models of NSCLC. Reference: |