CAS NO: | 29080-58-8 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Cas No. | 29080-58-8 |
别名 | 木犀草素-7,3',4'-三甲醚; 5-Hydroxy-3',4',7-trimethoxyflavone |
Canonical SMILES | OC1=C2C(OC(C3=CC=C(OC)C(OC)=C3)=CC2=O)=CC(OC)=C1 |
分子式 | C18H16O6 |
分子量 | 328.32 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) is a flavonoid from the herb Lippia nodiflora L. (Verbenaceae) which has been documented to exhibit anti-inflammatory, antipyretic, antitussive, antidiabetic, anticancer, and antimelanogenesis properties. 7,3',4'-Tri-O-methylluteolin obviously reduces the prodn of pro-inflammatory cytokines, such as TNF-α, IL-6, and IL-1β in a concentration-dependent manner. 7,3',4'-Tri-O-methylluteolin significantly induces reduction in the mRNA expressions of inducible nitric oxide synthase and cyclooxygenase-2, representing that inhibition occurs at the transcriptional level[1]. TNF-α IL-6 IL-1β [1]. Sudha, A, et al. Protective effect of 5-hydroxy-3′,4′,7-trimethoxyflavone against inflammation induced by lipopolysaccharide in RAW 264.7 macrophage: in vitro study and in silico validation. Medicinal Chemistry Research, 2016,25(9), 1754-1767. |