CAS: | 1936422-33-1 |
分子式: | C27H33F2N7O2 |
分子量: | 525.59 |
纯度: | >98% |
溶解性: | DMSO |
存储: | -20℃, stored under nitrogen. In solvent : -80℃, 6 months; -20℃, 1 month (stored under nitrogen) |
研究领域: | Cancer |
Target: | IC50: 0.94 nM (CBP), 6.2 nM (BRET), 5100 nM (BRD4(1)) |
描述: | GNE-781 is a highly potent and selective CBP inhibitor with an IC50 of 0.94 nM in TR-FRET assay. GNE-781 also inhibits BRET and BRD4(1) with IC50s of 6.2 nM and 5100 nM, respectively. |