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Resveratrol-3-O-Sulfate(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Resveratrol-3-O-Sulfate(sodium salt)图片
CAS NO:858127-11-4
包装与价格:
包装价格(元)
500μg电议
1mg电议

产品介绍
Resveratrol-3-O-sulfate (sodium) 是白藜芦醇的代谢物。
Cas No.858127-11-4
Canonical SMILESO=S(OC1=CC(O)=CC(/C=C/C2=CC=C(O)C=C2)=C1)([O-])=O.[Na+]
分子式C14H11O6S•Na
分子量330.3
溶解度DMSO: Slightly Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Resveratrol-3-O-sulfate is a metabolite of resveratrol . In U-937 cells stimulated with LPS, resveratrol-3-O-sulfate (1 µM) decreases the expression of IL-1α, IL-1β, and IL-6 by 61.2, 76.6, and 42.2%, respectively, and decreases the release of TNF-α and IL-6 to similar levels as resveratrol. It has antioxidant activity in a Trolox assay, dose-dependently decreases growth of Caco-2 colorectal adenocarcinoma cells when used at concentrations ranging from 10 to 100 µM, and induces apoptosis at concentrations of 25 and 50 µM. Resveratrol-3-O-sulfate also displaces rosiglitazone from the outer mitochondrial protein mitoNEET (IC50 = 3.36 µM for the human protein), indicating that it binds to the thiazolidine-2,4-dione (TZD) binding pocket.