IWP 12 是一种有效的豪猪 (PORCN) 抑制剂，抑制细胞自主 Wnt 信号传导，IC50 为 15 nM。
| Cas No. | 688353-45-9 |
| 化学名 | 2-((3,6-dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(5-methylbenzo[d]thiazol-2-yl)acetamide |
| Canonical SMILES | O=C1C2=C(CC(C)S2)N=C(SCC(NC3=NC(C=CC(C)=C4)=C4S3)=O)N1C |
| 分子式 | C18H18N4O2S3 |
| 分子量 | 418.56 |
| 溶解度 | DMF: 5 mg/ml,DMF:PBS(pH7.2) (1:2): 0.3 mg/ml,DMSO: 2 mg/ml |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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