| CAS NO: | 59-46-1 |
| 包装: | 50mg |
| 市场价: | 504元 |
| Cas No. | 59-46-1 |
| 别名 | 普鲁卡因 |
| 化学名 | 2-(diethylamino)ethyl 4-aminobenzoate |
| Canonical SMILES | CCN(CC)CCOC(=O)C1=CC=C(C=C1)N |
| 分子式 | C13H20N2O2 |
| 分子量 | 236.31 |
| 溶解度 | ≥ 8.7mg/mL in DMSO with gentle warming |
| 储存条件 | Store at -20°C,unstable in solution, ready to use. |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Procaine is a local anesthetic drug of the amino ester group, which acts through multiple targets.Target: OthersProcaine is a local anesthetic of the ester type that has a slow onset and a short duration of action.Procaine (0.01-100 microM) inhibited the 5-HT3 receptor-mediated inward current in the whole-cell patch clamp recording. Procaine appears to produce a competitive inhibition on 5-HT3 receptors with a KD of 1.7 microM [1]. Procaine is a DNA-demethylating agent that produces a 40% reduction in 5-methylcytosine DNA content as determined by high-performance capillary electrophoresis or total DNA enzyme digestion. Procaine can also demethylate densely hypermethylated CpG islands. Procaine also has growth-inhibitory effects in these cancer cells, causing mitotic arrest [2]. Procaine functions as an excitant of limbic system cells, and that procaine alters synaptic transmission in some, but not all, output pathways from the amygdale [3]. References: |
m.cnreagent.com