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Nafamostat
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Nafamostat图片
CAS NO:81525-10-2
包装与价格：
包装价格(元)
10mg电议
50mg电议

产品介绍
Nafamostat 是一种合成丝氨酸蛋白酶抑制剂，是一种抗凝剂。
Cas No.81525-10-2
别名萘莫司他
化学名(6-carbamimidoylnaphthalen-2-yl) 4-(diaminomethylideneamino)benzoate
Canonical SMILESC1=CC(=CC=C1C(=O)OC2=CC3=C(C=C2)C=C(C=C3)C(=N)N)N=C(N)N
分子式C19H17N5O2
分子量347.37
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Nafamostat, a synthetic serine protease inhibitor, is an anticoagulant. Nafamostat supresses T cell auto-reactivity by decreasing granzyme activity and CTL cytolysis[1][2][3].

References:
[1]. Ikehara S, et al. Effect of FUT-175, a new synthetic protease inhibitor, on the development of lupus nephritis in (NZB x NZW) F1 mice. Immunology. 1985 Aug;55(4):595-600.
[2]. Homma S, et al. Nafamostat mesilate, a serine protease inhibitor, suppresses interferon-gamma-induced up-regulation of programmed cell death ligand 1 in human cancer cells. Int Immunopharmacol. 2018 Jan;54:39-45.
[3]. Pak K, et al. Effectiveness of FUT-175, protease inhibitor, as an anticoagulant to hemodialysis. Hinyokika Kiyo. 1988 Jun;34(6):1077-81.