CAS NO: | 1192224-24-0 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Cas No. | 1192224-24-0 |
Canonical SMILES | O[C@@H](CNNC([C@@H](NC(OC)=O)C(C)(C)C)=O)[C@@H](NC([C@H](C(C)(C)C)NC(OC)=O)=O)CC1=CC=CC=C1 |
分子式 | C26H43N5O7 |
分子量 | 537.7 |
溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Des(benzylpyridyl) atazanavir is a major metabolite of the HIV-1 protease inhibitor atazanavir .1,2 It is formed from atazanavir by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2D6.2 |1. ter Heine, R., Hillebrand, M.J.X., Rosing, H., et al. Identification and profiling of circulating metabolites of atazanavir, a HIV protease inhibitor. Drug Metab. Dispos. 37(9), 1826-1840 (2009).|2. Li, F., Lu, J., Wang, L., et al. CYP3A-mediated generation of aldehyde and hydrazine in atazanavir metabolism. Drug Metab. Dispos. 39(3), 394-401 (2011). |