CAS: | 1644443-47-9 |
分子式: | C14H11ClN6O3 |
分子量: | 346.73 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Neurological Disease;Cancer |
Target: | IC50: 19 nM (VPS34), 90 nM (starvation-induced autophagy)[1] |
描述: | Autophinib is a potent autophagy inhibitor, which can inhibit autophagy induced by starvation by targeting the lipid kinase VPS34 with IC50s of 90, 40 and 19 nM, respectively. |