K03861
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
产品介绍
CAS: | 853299-07-7 |
分子式: | C24H26F3N7O2 |
分子量: | 501.50 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | CDK2(C118L/A144C)9.7 nM (Kd)CDK2(A144C):15.4 nM (Kd);CDK2(C118L):18.6 nM (Kd);CDK2(WT):50 nM (Kd);CDK2(C118L/A144C-Cyclin B):134.1 nM (Kd) |
描述: | K03861 (AUZ 454) is a type II CDK2 inhibitor with Kd of 8.2 nM. AUZ 454 (K03861) inhibits CDK2 activity by competing with binding of activating cyclins. |