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Phen-DC3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Phen-DC3图片
CAS NO:942936-75-6
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍

Phen-DC3是一个G4特异性配体,可以抑制解旋酶FANCJ和DinG且IC50s值分别为65±6和50±10nM。

Cas No.942936-75-6
Canonical SMILESC[N+]1=C2C=CC=CC2=CC(NC(C3=CC=C4C=CC5=CC=C(C(NC6=C[N+](C)=C7C=CC=CC7=C6)=O)N=C5C4=N3)=O)=C1
分子式C34H26N6O2
分子量550.61
溶解度DMSO : ≥ 34 mg/mL (61.75 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65±6 and 50±10 nM, respectively.

[1]. Bharti SK, et al. Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability. J Biol Chem. 2013 Sep 27; 288(39):28217-29.