Talazoparib(BMN-673 LT-673)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
包装与价格:
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
产品介绍
产品名称: | 他拉唑帕利 |
CAS: | 1207456-01-6 |
分子式: | C19H14F2N6O |
分子量: | 380.35 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
Target: | IC50: 0.57 nM (PARP1)[1]Ki: 1.2/0.87 nM (PARP1/2)[1] |
描述: | Talazoparib (BMN 673) is a novel PARP inhibitor with IC50 of 0.57 nM for PARP1 in a cell-free assay. It is also a potent inhibitor of PARP-2, but does not inhibit PARG and is highly sensitive to PTEN mutation. |