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G0507
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
G0507图片
CAS NO:1223998-29-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
G0507 是吡咯并嘧啶二酮化合物,一种有效的 LolCDE ABC 转运蛋白抑制剂。G0507 是大肠杆菌生长的抑制剂,并诱导胞浆外 σE 应激反应。G0507 用作解剖革兰氏阴性细菌中脂蛋白运输的化学探针。
Cas No.1223998-29-5
Canonical SMILESO=C1NC(NC(C2=CC=C(C)S2)=C3C4=CC=C(OC)C=C4)=C3C(N1)=O
分子式C18H15N3O3S
分子量353.4
溶解度DMSO: 5 mg/mL (14.15 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

G0507, a pyrrolopyrimidinedione compound, is a potent LolCDE ABC Transporter inhibitor. G0507 is a inhibitor of Escherichia coli growth and induces the extracytoplasmic σE stress response. G0507 acts as a chemical probe to dissect lipoprotein trafficking in Gram-negative bacteria[1].

[1]. Nickerson NN, et al. A Novel Inhibitor of the LolCDE ABC Transporter Essential for Lipoprotein Trafficking in Gram-Negative Bacteria. Antimicrob Agents Chemother. 2018 Mar 27;62(4).