CAS NO: | 1798310-55-0 |
包装 | 价格(元) |
500μg | 电议 |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Cas No. | 1798310-55-0 |
化学名 | N-(2,5-dichlorophenyl)-4-(2-furanyl)-1,4,5,6,7,8-hexahydro-2-methyl-5-oxo-3-quinolinecarboxamide |
Canonical SMILES | ClC1=CC(NC(C2=C(C)NC(CCCC3=O)=C3C2C4=CC=CO4)=O)=C(Cl)C=C1 |
分子式 | C21H18Cl2N2O3 |
分子量 | 417.3 |
溶解度 | 5mg/mL in DMSO, 2mg/mL in DMF |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
文献引用 | |
产品描述 | Free fatty acid receptor 3 (FFAR3; GPR41) is a G protein-coupled receptor activated by short chain fatty acids (SCFAs). It is expressed in adipose tissue, the gastrointestinal tract, and the peripheral nervous system, and it is involved in SCFA-dependent energy regulation.[1] AR420626 is a selective agonist of FFAR3 (GPR41; IC50 = 117 nM) that does not activate the related receptor FFAR2 (GPR43) at concentrations up to 100 µM.[2] At 10 µM, it can stimulate a 1.26-fold increased release of glucagon-like peptide-1 from colonic crypt cultures.[3] Reference: |