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ThioGlo1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ThioGlo1图片
CAS NO:137350-66-4
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议
250mg电议

产品介绍
A thiol-reactive fluorescent probe
Cas No.137350-66-4
别名(10-甲基-2,5-二氧-2,5-二氢-1H-吡咯-1-基)-9-甲氧基-3-氧代-3H-苯并[F]色烯-2-羧酸
Canonical SMILESCOC1=CC=C(C=CC(O2)=C3C=C(C(OC)=O)C2=O)C3=C1N4C(C=CC4=O)=O
分子式C20H13NO7
分子量379.3
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

ThioGlo1 is a thiol-reactive fluorescent probe.1,2,3Upon reaction with a thiol group, a fluorescent adduct is formed that displays excitation/emission maxima of 384/513 nm, respectively.2,3It also reacts with sulfite to form a fluorescent adduct with similar spectral characteristics, and interference from sulfite during thiol determination must be accounted for using secondary methods. ThioGlo1 has been used to monitor the oxidative stability of beer.

1.Yang, J.-R., and Langmuir, M.E.Synthesis and properties of a maleimide fluorescent thiol reagent derived from a naphthopyranoneJ. Heterocycl. Chem.28(5)1177-1180(1991) 2.Hoff, S., Larsen, F.S., Anderson, M.L., et al.Quantification of protein thiols using ThioGlo 1 fluorescent derivatives and HPLC separationAnalyst138(7)2096-2103(2013) 3.Lund, M.N., and Andersen, M.L.Detection of thiol groups in beer and their correlation with oxidative stabilityJ. Am. Soc. Brew. Chem.69(3)163-169(2011)