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Isoxicam
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Isoxicam图片
CAS NO:34552-84-6
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
100mg电议
250mg电议

产品介绍
Isoxicam 是一种口服有效的非甾体抗炎剂,可用于关节炎的研究。Isoxicam 是一种非选择性的 COX-1 和 COX-2 抑制剂。
Cas No.34552-84-6
别名伊索昔康
Canonical SMILESO=C(C1=C(O)C2=CC=CC=C2S(N1C)(=O)=O)NC3=NOC(C)=C3
分子式C14H13N3O5S
分子量335.34
溶解度DMSO: 5 mg/mL (14.91 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Isoxicam is an orally active, long-acting, non-steroidal anti-inflammatory agent for the research of arthritis[1]. Isoxicam is a nonselective inhibitor of COX-1 and COX-2[2].

[1]. DiPasquale G, et al. The antiinflammatory properties of isoxicam (4-hydroxy-2methyl-N-(5-methyl-3isoxolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide). Agents Actions. 1975 Aug;5(3):256-63. [2]. Xu S, et al. Oxicams bind in a novel mode to the cyclooxygenase active site via a two-water-mediated H-bonding Network. J Biol Chem. 2014 Mar 7;289(10):6799-808.