CAS NO: | 486-21-5 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
20mg | 电议 |
Cas No. | 486-21-5 |
别名 | 异嗪皮啶 |
Canonical SMILES | O=C1C=CC2=CC(OC)=C(O)C(OC)=C2O1 |
分子式 | C11H10O5 |
分子量 | 222.19 |
溶解度 | DMSO: 250 mg/mL (1125.16 mM) |
储存条件 | Store at -20°C,protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells[1]. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2]. [1]. Yamazaki T, et al. Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits matrix metalloproteinase-7 expression and cell invasion of human hepatoma cells.Biol Pharm Bull. 2010;33(10):1716-22. [2]. Jin J , et al. Isofraxidin targets the TLR4/MD-2 axis to prevent osteoarthritis development.Food Funct. 2018 Nov 14;9(11):5641-5652. |