CAS: | 2007885-39-2 |
分子式: | C18H17F4N3O3 |
分子量: | 399.34 |
纯度: | >98% |
溶解性: | DMSO : ≥ 130 mg/mL (325.54 mM) |
存储: | 4℃, stored under nitrogen. In solvent : -80℃, 6 months; -20℃, 1 month (stored under nitrogen) |
研究领域: | Inflammation/Immunology |
Target: | IC50: 0.10 μM (Mouse LOXL2), 0.12 μM (Rat LOXL2), 0.16 μM (Dog LOXL2), 0.71 μM (hLOXL2), 1.17 μM (hLOXL3) |
描述: | PAT-1251 is a potent, selective and oral Lysyl Oxidase-Like 2 (LOXL2) inhibitor, with IC50 values of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively. PAT-1251 also potently inhibits mouse, rat, a |