Citromycetin 是一种来自澳大利亚海洋和陆地青霉属的芳香族聚酮化合物。
Cas No. | 478-60-4 |
别名 | 柠檬菌素 |
Canonical SMILES | OC1=C(O)C=C(OCC2=C3OC(C)=CC2=O)C3=C1C(O)=O |
分子式 | C14H10O7 |
分子量 | 290.2 |
溶解度 | DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Citromycetin is a fungal metabolite originally isolated from P. frequentans with antibiotic activity against the Gram-positive bacteria S. aureus and the Gram-negative bacteria V. cholerae and S. flexneri (MICs = 64 µg/ml for both). Citromycetin is selectively cytotoxic to cancerous cells over non-cancerous cells (LC50s = 9.21 and 261.14 µg/ml for HeLa and Vero cells, respectively). Formulations containing citromycetin have been studied for use in the treatment of amyloidosis and α-synuclein fibril diseases. |