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1,2,3-Trilinoleoyl-rac-glycerol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
1,2,3-Trilinoleoyl-rac-glycerol图片
CAS NO:537-40-6
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议
1g电议

产品介绍
1,2,3-Trilinoleoyl-rac-glycerol 是一种内源性代谢物。
Cas No.537-40-6
别名甘油三亚油酸酯
Canonical SMILESO=C(CCCCCCC/C=C\C/C=C\CCCCC)OCC(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCC/C=C\C/C=C\CCCCC)=O
分子式C57H98O6
分子量879.4
溶解度DMF: 10 mg/ml,Ethanol: 10 mg/ml,Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

1,2,3-Trilinoleoyl-rac-glycerol is a triacylglycerol that contains linoleic acid at the sn-1, sn-2, and sn-3 positions. It reduces production of oxygen-derived free radicals in leukocytes.1 1,2,3-Trilinoleoyl-rac-glycerol (1 μM) reduces mitochondrial swelling and deformation induced by ischemia and reperfusion injury in perfused rat hearts. In vivo, 1,2,3-trilinoleoyl-rac-glycerol (1 mg/kg) reduces the incidence rate and duration of ventricular tachycardia, as well as infarct size in a rat model of coronary artery ligation-induced ischemia and reperfusion injury.2

|1. Chan, P., Niu, C.-S., Cheng, J.-T., et al. Trilinolein preserves mitochondria ultrastructure in isolated rat heart subjected to global ischemia through antioxidant activity as measured by chemiluminescence. Pharmacology 52(4), 216-225 (1996).|2. Chan, P., Tsai, S.-K., Chiang, B.-N., et al. Trilinolein reduces infarct size and suppresses ventricular arrhythmias in rats subjected to coronary ligation. Pharmacology 51(2), 118-126 (1995).