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Isonicotinic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Isonicotinic acid图片
CAS NO:55-22-1
包装与价格:
包装价格(元)
100mg电议
200mg电议
500mg电议

产品介绍
Isonicotinic acid 是 Isoniazid 的代谢产物。通过肼解将 Isoniazid 转化为 Isonicotinic acid,并且 Isoniazid 向 Isonicotinic acid 的生物转化也可以通过细胞色素 P450 (CYP) 酶 (如 CYP2C) 催化。
Cas No.55-22-1
别名异烟酸
Canonical SMILESO=C(O)C1=CC=NC=C1
分子式C6H5NO2
分子量123.11
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Isonicotinic acid is a metabolite of Isoniazid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the Isoniazid to Isonicotinic acid biotransformation also to be catalyzed by cytochrome P450 (CYP) enzymes, e.g., CYP2C[1].

[1]. Seng KY, et al. Population pharmacokinetic analysis of isoniazid, acetylisoniazid, and isonicotinic acid in healthy volunteers. Antimicrob Agents Chemother. 2015 Nov;59(11):6791-9.