CAS NO: | 518-28-5 |
包装 | 价格(元) |
50mg | 电议 |
100mg | 电议 |
500mg | 电议 |
Cas No. | 518-28-5 |
别名 | 鬼臼毒素; Podophyllotoxin |
化学名 | 9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one |
Canonical SMILES | COC1=CC(C2C3C(C(O)C4=CC5=C(OCO5)C=C24)COC3=O)=CC(OC)=C1OC |
分子式 | C22H22O8 |
分子量 | 414.41 |
溶解度 | DMF: 15 mg/ml,DMSO: 15 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml,Ethanol: 0.14 mg/ml,PBS (pH 7.2): slightly soluble |
储存条件 | Store at 2-8°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II. Podophyllotoxin, a kind of non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum plant, has been shown to inhibit the growth of various carcinoma cells. Podophyllotoxin is a natural product that inhibits the polymerization of tubulin and has served as a prototype for the development of diverse antitumor agents in clinical use. References: |