Description: TH-5427 (TH5427) is a novel, potent, and selective NUDT5 inhibitor (IC50=29 nM) with anticancer activity.
References: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells [published correction appears in Nat Commun. 2019 Nov 1;10(1):5050]. Nat Commun. 2018;9(1):250.