PCSK9 degrader 1 is a degrader of proprotein convertase substilisin-like/kexin type 9 (PCSK9) with lipid-lowering effects. PCSK9 is a serine protease involved in a protein-protein interaction with the low-density lipoprotein (LDL) receptor that has both human genetic and clinical validation. Blocking this protein-protein interaction prevents LDL receptor degradation and thereby decreases LDL cholesterol levels.
纯度:≥98%
CAS:2215931-60-3