| CAS NO: | 51093-55-1 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 405.41 |
| Cas No. | 51093-55-1 |
| Formula | C18H23N5O6 |
| Solubility | ≥24.25 mg/mL in DMSO |
| Chemical Name | 8-(dimethylamino)-7-methyl-10-((2S,3S,4R)-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione |
| Canonical SMILES | O=C(C1=NC2=CC(C)=C(N(C)C)C=C2N(C[C@H](O)[C@H](O)[C@H](O)CO)C1=N3)NC3=O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
Roseoflavin is an analog of flavin mononucleotide (FMN) and riboflavin that is synthesized by the soil bacterium S. davawensis and possesses antimicrobial activity[1].
Roseoflavin has been shown to bind directly to FMN riboswitch aptamers (KD = ~100 nM), downregulating the expression of genes responsible for the synthesis and transport of riboflavin[2].
References：
[1]. Langer S, Hashimoto M, Hobl B, et al. Flavoproteins are potential targets for the antibiotic roseoflavin in Escherichia coli. Journal of Bacteriology, 2013, 195(18): 4037-4045.
[2]. Lee E R, Blount K F, Breaker R R. Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression. RNA Biol, 2009, 6(2): 187-194.
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