描述
| Gene ID: | 10135 | Accession #: | P43490 |
| Alternate Names: | Human Visfatin, Visfatin, h-Visfatin, rh-Visfatin, recombinant human Visfatin, recombinant Visfatin |
| Source: | Escherichia Coli. | M.Wt: | 55.0 kDa |
| Appearance: | Lyophilized protein | Storage: | Store at -20°C |
| Formulation: | Lyophilized with no additives. |
| Solubility: | Reconstitute in PBS to the concentration of 0.1-1 mg/ml. |
| Shipping Condition: | Gel pack. | Handling: | Centrifuge the vial prior to opening. |
| Usage: | For Research Use Only! Not to be used in humans. |
资料参考
Nicotinamide phosphoribosyltransferase (also known as PBEF1 or visfatin) is an enzyme that is encoded by the PBEF1 gene in humans. This protein has also been reported as a cytokine (PBEF) which promotes B cell maturation and inhibits neutrophil apoptosis. This protein is an adipokine that is localized to the bloodstream and has lots of functions, including inhibition of neutrophil apoptosis and the promotion of vascular smooth muscle cell maturation. It also has insulin-mimetic effects, improving insulin sensitivity and lowering blood glucose. This protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. 生物活性
| Mimics insulin effects in differentiating 3T3-L1 cells. |
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