| CAS NO: | 925676-48-8 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 20mg | 电议 |
| Cas No. | 925676-48-8 |
| Canonical SMILES | FC1=CN=CC=C1C(N=CC(NC(C2CC2)=O)=N3)=C3C4=CC=CN=C4 |
| 分子式 | C18H14FN5O |
| 分子量 | 335.34 |
| 溶解度 | DMSO : ≥ 125 mg/mL (372.76 mM);Water :< 0.1 mg/mL (insoluble) |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | LAS101057 is a potent, selective, and orally efficacious A2B receptor antagonist. At 3 mg/kg, LAS101057 is active in preventing methacholine-induced AHR, and at 10 mg/kg it inhibits AHR to methacholine to a level virtually equal to that seen with dexamethasone at 1 mg/kg[1]. [1]. Paul Eastwood, et al. Discovery of LAS101057: A Potent, Selective, and Orally Efficacious A2B Adenosine Receptor Antagonist. ACS Med Chem Lett. 2011 Mar 10; 2(3): 213-218. |
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