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CB2R-IN-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CB2R-IN-1图片
CAS NO:1257555-79-5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
CB2R-IN-1是一种有效的cannabinoidCB2受体反向激动剂,Ki为0.9nM。
Cas No.1257555-79-5
Canonical SMILESO=S(C(F)(F)F)(NCC1(CCC)CCN(S(=O)(C(N2S(=O)(C3=NC=CC=C3)=O)=CC4=C2C=CC=C4)=O)CC1)=O
分子式C23H27F3N4O6S3
分子量608.67
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CB2R-IN-1 is a potent cannabinoid CB2 receptor inverse agonist with a Ki of 0.9 nM.

CB2R-IN-1 (Compound 37) is a potent cannabinoid CB2 receptor ligand (Ki=0.9 nM) with excellent selectivity over the CB1 receptor (Ki=8259.3 nM)[1].

[1]. Tong L, et al. Expansion of SAR studies on triaryl bis sulfone cannabinoid CB2 receptor ligands. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6785-9.