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Metronidazole-d4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Metronidazole-d4图片
CAS NO:1261392-47-5
包装:1mg
市场价:4460元

产品介绍
An internal standard for the quantification of metronidazole
Cas No.1261392-47-5
别名甲硝唑 d4
Canonical SMILESCC1=NC=C([N+]([O-])=O)N1C([2H])([2H])C([2H])([2H])O
分子式C6H5D4N3O3
分子量175.2
溶解度DMF: 15 mg/ml,DMSO: 15 mg/ml,Ethanol: 5 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Metronidazole-d4is intended for use as an internal standard for the quantification of metronidazole by GC- or LC-MS. Metronidazole is an antibiotic that has activity against anaerobic bacteria and protozoa includingT. vaginalis, E. histolytica, G. lamblia, C. difficile, andH. pylori.1It reduces the growth ofE. coli in vitro(MIC = 128 mg/L under anaerobic conditions).2In vivo, metronidazole reduces viable counts ofB. fragilisin a rabbit model of infection. Formulations containing metronidazole have been used in the treatment of various infections includingH. pyloriandC. difficile.

1.Samuelson, J.Why metronidazole is active against both bacteria and parasitesAntimicrob. Agents Chemother.43(7)1533-1541(1999) 2.Rylander, M., Holm, S.E., Brorson, J.-E., et al.Activity of metronidazole on Bacteroides fragilis and/or Escherichia coli in vitro and in vivoJ. Antimicrob. Chemother.7(3)257-267(1981)