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Homodestcardin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Homodestcardin图片
CAS NO:917382-84-4
包装:1mg
市场价:4158元

产品介绍
Homodestcardin 是一种基于 destruxin 的环缩肽，是一种免疫抑制剂。
Cas No.917382-84-4
Canonical SMILESO=C([C@@H](CC(C)C)OC1=O)N2[C@]([C@@H](C)CC2)([H])C(N[C@]([C@@H](C)CC)([H])C(N(C)[C@@](C(N([C@H](C(NCC1)=O)C)C)=O)([H])[C@@H](C)CC)=O)=O
分子式C32H55N5O7
分子量621.8
溶解度Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Homodestcardin is a cyclic depsipeptide fungal metabolite that has been found inT. roseumand has immunosuppressant activity.1It inhibits concanavalin A-induced proliferation of isolated mouse T cells (IC50= 0.86 µM).

1.Zhang, A.H., Wang, X.Q., Han, W.B., et al.Discovery of a new class of immunosuppressants from Trichothecium roseum co-inspired by cross-kingdom similarity in innate immunity and pharmacophore motifChem. Asian J.8(12)3101-3107(2013)