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Licochalcone B
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Licochalcone B图片
CAS NO:58749-23-8
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
Licochalcone B 是从 Glycyrrhiza inflate 根中提取的。Licochalcone B 抑制淀粉样蛋白 β (amyloid β; Aβ420) 自聚集作用 (IC50=2.16 μM) 并分解预先形成的 Aβ42 原纤维,通过螯合金属离子减少金属诱导的 Aβ42 聚集。
Cas No.58749-23-8
别名甘草查尔酮 B
Canonical SMILESO=C(C1=CC=C(O)C=C1)/C=C/C2=CC=C(O)C(O)=C2OC
分子式C16H14O5
分子量286.28
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Licochalcone B is an extract from the root of Glycyrrhiza inflate. Licochalcone B inhibits amyloid β (Aβ42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation through chelating metal ions[1].

[1]. Cao Y, et al. Licochalcone B, a chalcone derivative from Glycyrrhiza inflata, as a multifunctional agent for the treatment of Alzheimer's disease. Nat Prod Res. 2018 Oct 22:1-4.