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SKF96067
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SKF96067图片
CAS NO:115607-61-9
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
SKF96067是一种可逆的H+/K+-ATPase抑制剂。
Cas No.115607-61-9
Canonical SMILESCCCC(C1=C(NC2=CC=CC=C2C)C3=CC=CC(OC)=C3N=C1)=O
分子式C21H22N2O2
分子量334.41
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

SKF96067 is a reversible inhibitor of the gastric H+/K+-ATPase.

SKF96067 inhibits K+-stimulated ATPase activity competitively with respect to the activating action K+, with a Ki value of 0.39 ± 0.05 μM. SKF96067 also inhibits hydrogen ion transport. SKF96067 inhibits ATPase activity with an IC50 value of 60 ± 10 μM at pH 7.0, in the presence of 100 mM NaCl and 1 mM KCl[1].

[1]. Keeling DJ, et al. SK&F 96067 is a reversible, lumenally acting inhibitor of the gastric (H+ + K+)-ATPase. Biochem Pharmacol. 1991 Jun 21;42(1):123-30.