您好，欢迎来到化工原料网！ [登录] [免费注册]
化工原料网
发布求购
位置：首页 > 产品库 > Fmoc-Lys(biotin-PEG4)-OH
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Fmoc-Lys(biotin-PEG4)-OH
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Fmoc-Lys(biotin-PEG4)-OH图片
CAS NO:1334172-64-3
包装:100mg
市场价:1599元

产品介绍
Fmoc-Lys (biotin-PEG4)-OH 是一种生物素标记的 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。
Cas No.1334172-64-3
分子式C42H59N5O11S
分子量842.01
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Fmoc-Lys (biotin-PEG4)-OH is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.