CAS NO: | 59870-65-4 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
Cas No. | 59870-65-4 |
别名 | 光甘草醇 |
Canonical SMILES | O=C1C[C@@H](C2=CC=C(O)C(C/C=C(C)\C)=C2)OC3=C(C/C=C(C)\C)C(O)=CC=C13 |
分子式 | C25H28O4 |
分子量 | 392.49 |
溶解度 | Soluble in DMSO |
储存条件 | 4°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity[1]. Glabrol (Compound 1) decreases cholesteryl ester formation with an IC50 value of 26.0 μM in HepG2 cells[1]. [1]. Choi JH, et al. Glabrol, an acyl-coenzyme A: cholesterol acyltransferase inhibitor from licorice roots. J Ethnopharmacol. 2007 Apr 4;110(3):563-6. |