CAS NO: | 18331-34-5 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
Cas No. | 18331-34-5 |
Canonical SMILES | S=C(N(CC)C/1=O)SC1=C/C2=CC=CC=C2 |
分子式 | C12H11NOS2 |
分子量 | 249.35 |
溶解度 | DMSO : 25 mg/mL (100.26 mM);Water :< 0.1 mg/mL (insoluble) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | BTR-1 is an active anti-cancer agent, causes S phase arrest, and affects DNA replication in leukemic cells. BTR-1 activates apoptosis and induces cell death[1]. Apoptosis[1] BTR-1 (10, 50, 100, and 250 µM, 5 days) dose-dependently causes cytotoxicity in human leukemic cells, with IC50s of 8 and 6 µM at 48 and 72 h, respectively[1]. Cell Viability Assay[1] Cell Line: T-cell leukemic cell lines [1]. Moorthy BT, et al. Novel rhodanine derivatives induce growth inhibition followed by apoptosis. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6297-301. |