CAY10698 is a novel and potent 12-LO inhibitor ( IC50 =5.1 μM). It demonstrates greatly reduced potency for 15-LO-1, 15-LO-2, and 5-LO (IC50s = >50, >40, and >200 μM. The scaffold of this compound has been subjected to medicinal chemistry optimization and biological characterization for development of potential 12-LO inhibitors.
纯度:≥98%
CAS: 684236-01-9