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Lithocholic Acid 3-sulfate(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Lithocholic Acid 3-sulfate(sodium salt)图片
CAS NO:64936-81-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍

Lithocholic acid 3-sulfate is a metabolite of the secondary bile acid lithocholic acid.

Cas No.64936-81-8
别名牛磺胆酸-3-硫酸酯二钠盐,Lithocholate 3-sulfate
化学名(3α,5β)-3-(sulfooxy)-cholan-24-oic acid, disodium salt
Canonical SMILES[O-]C(CC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](OS([O-])(=O)=O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C)=O.[Na+].[Na+]
分子式C24H38O6S o 2Na
分子量500.6
溶解度Methanol: 1 mg/mL,Water: 5 mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Lithocholic acid 3-sulfate is a metabolite of the secondary bile acid lithocholic acid.[1] It is water soluble and the primary form of lithocholic acid in the bile duct. Lithocholic acid 3-sulfate forms a complex with calcium in vitro.[2] Biliary secretion of lithocholic acid 3-sulfate is increased in a rat model of diabetes induced by streptozotocin.[3]

Reference:
[1]. Borriello, S.P., and Owen, R.W. The metabolism of lithocholic acid and lithocholic acid-3-α-sulfate by human fecal bacteria. Lipids 17(7), 477-482 (1982).
[2]. Oelberg, D.G., Dubinsky, W.P., Adcock, E.W., et al. Calcium binding by lithocholic acid derivatives. Am. J. Physiol. 247(1 Pt 1), G112-G115 (1984).
[3]. Kirkpatrick, R.B., and Kraft, B.G. Effect of streptozotocin-induced diabetes on bile acid sulfation in male rat liver. Am. J. Physiol. 247(3 Pt 1), G226-G230 (1984).