Lansoprazole sulfone is a phase I metabolite of lansoprazole.
Cas No. | 131926-99-3 |
别名 | 兰索拉唑磺酸盐 |
Canonical SMILES | CC1=C(CS(C2=NC(C=CC=C3)=C3N2)(=O)=O)N=CC=C1OCC(F)(F)F |
分子式 | C16H14F3N3O3S |
分子量 | 385.4 |
溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 5 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Lansoprazole sulfone is a phase I metabolite of lansoprazole . Lansoprazole is a proton pump inhibitor that inactivates the hydrogen/potassium-stimulated ATPase pumps in parietal cells, thus inhibiting gastric acid secretion and increasing intragastric pH. Lansoprazole is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form lansoprazole sulfone. |