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Bikaverin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Bikaverin图片
CAS NO:33390-21-5
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
比卡维林 (Lycopersin) 是一种由不同真菌种类产生的微红色色素。
Cas No.33390-21-5
别名比卡菌素,Lycopersin
Canonical SMILESO=C(C=C1OC)C2=C(C(O)=C(OC(C=C(OC)C=C3C)=C3C4=O)C4=C2O)C1=O
分子式C20H14O8
分子量382.3
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Bikaverin is a fungal metabolite originally isolated from F. oxysporum f. sp. lycopersici that has diverse biological activities, including antiprotozoal, nematocidal, antiproliferative, and fungicidal properties.1,2,3,4 It is active against L. braziliensis when used at a concentration of 0.15 μg/ml and against B. xylophilus at a concentration of 100 μg/ml.2 It inhibits proliferation of NCI-H460, MIA PaCa-2, MCF-7, and SF-268 cells (IC50s = 0.43, 0.26, 0.42, and 0.38 μM, respectively).3 Bikaverin inhibits the growth of certain plant pathogenic fungi, including R. solani, P. capsici, P. infestans, and M. grisea (IC50s =<1.2, 10, 60, and 70 μg/ml, respectively).4 It inhibits the development and provides disease control of tomato late blight and wheat leaf rust caused by P. infestans and P. recondita, respectively, when applied at a concentration of 300 μg/ml.

References
1. Nord, F.F. Structure of some Fusarium pigments and their action. Intern. Congr. Biochem., Abstrs. of Communs. 1st Congr. Cambridge, Engl. 243-244 (1949).
2. LimÓn, M.C., RodrÍguez-Ortiz, R., and Avalos, J. Bikaverin production and applications. Appl. Microbiol. Biotechnol. 87(1), 21-29 (2010).
3. Zhan, J., Burns, A.M., Liu, M.X., et al. Search for cell motility and angiogenesis inhibitors with potential anticancer activity: Beauvericin and other constituents of two endophytic strains of Fusarium oxysporum. J. Nat. Prod. 70(2), 227-232 (2007).
4. Son, S.W., Kim, H.Y., Choi, G.J., et al. Bikaverin and fusaric acid from Fusarium oxysporum show antioomycete activity against Phytophthora infestans. J. Appl. Microbiol. 104(3), 692-698 (2008).