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Caspase-7,human recombinant protein
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Caspase-7,human recombinant protein图片
包装与价格:
包装价格(元)
25 units电议
100 units电议

产品介绍

描述

Gene ID:840Accession #:P55210
Alternate Names:Active Human Caspase-7, Active Caspase-7, Caspase-7 Enzyme, Recombinant caspase-7, human caspase-7, human caspases, active caspases.
Source:Escherichia Coli.M.Wt:N/A
Appearance:Lyophilized powderStorage:Store at -70℃
Formulation:Lyophilized powder
Solubility:Reconstitute to 1 unit per μl in PBS containing 15% glycerol.
Shipping Condition:Gel pack.Handling:Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.

资料参考

Caspase-7 (also called Mch3, ICE-LAP3, CMH-1) belongs the caspase-family of cysteine proteases. Like other caspases, caspase-7 also exists as an inactive proenzyme in cells. Sequential activation of caspases plays a key role in the execution-phase of cell apoptosis. Caspases undergo proteolytic processing as inactive proenzymes by upstream caspases (caspase-8, -9) at conserved aspartic residues to produce two subunits, large one and small one. The two subunits dimerize to form the active enzyme in the form of a heterotetramer. Active caspase-7 has been shown involving in the proteolysis of poly ADP-ribose polymerase (PARP). PARP is involved in DNA repair and genomic maintenance. The precursor of this caspase is cleaved by caspase 10, caspase 3 and caspase 9. The recombinant active human caspase-7 was expressed in E. Coli.

生物活性

Specific activity> 25000 units/mg.