您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Caspase-8,human recombinant protein
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Caspase-8,human recombinant protein
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Caspase-8,human recombinant protein图片
包装:25 units
市场价:4690元

产品介绍

描述

Gene ID:841Accession #:Q14790
Alternate Names:Active Human Caspase-8, Active Caspase-8, Caspase-8 Enzyme, Recombinant caspase-8, human caspase-8, human caspases, active caspases.
Source:Escherichia Coli.M.Wt:N/A
Appearance:Lyophilized powderStorage:Store at -70℃
Formulation:Lyophilized powder
Solubility:Reconstitute to 1 unit per μl in PBS containing 15% glycerol.
Shipping Condition:Gel pack.Handling:Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.

资料参考

Caspase-8 (also called FLICE, MASH, Mch5) belongs to the caspase-family of cysteine proteases. Caspase-8 like other caspases also exists in cells as an inactive proenzyme. Sequential activation of caspases plays a key role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymescomposed of a prodomain, a large and a small protease subunit. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. Active caspase-8 has been demonstrated to activate caspase-3 leading to degradation of a various of cellular target proteins during apoptosis. The recombinant active human caspase-8 was expressed in E. coli.

生物活性

Specific activity> 5000 units/mg.