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Mafenide hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mafenide hydrochloride图片
CAS NO:138-37-4
包装:50mg
市场价:450元

产品介绍
Mafenide盐酸盐是一磺胺类抗生素化合物。
Cas No.138-37-4
别名盐酸磺胺米隆
Canonical SMILESO=S(C1=CC=C(CN)C=C1)(N)=O.[H]Cl
分子式C7H11ClN2O2S
分子量222.69
溶解度DMSO:44 mg/mL (197.58 mM) ; Water:44 mg/mL (197.58 mM); Ethanol:8 mg/mL (35.92 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Mafenide hydrochloride is a sulfonamide-type medication used as an antibiotic.Target: AntibacterialMafenide is a sulfonamide-type medication. Mafenide works by reducing the bacterial population present in the avascular tissues of burns and permits spontaneous healing of deep partial-thickness burns. It is used to treat severe burns. It is used topically as an adjunctive therapy for second- and third-degree burns. It is bacteriostatic against many gram-positive and gram-negative organisms, including Pseudomonas aeruginosa. Some sources state that mafenide is more appropriate for non-facial burns, while chloramphenicol/prednisolone or bacitracin are more appropriate for facial burns [1-3].

[1]. Siuda, J.F. and C.D. Cihonski, New compounds: carbamate derivatives of mafenide (homosulfanilamide). J Pharm Sci, 1972. 61(11): p. 1856-7. [2]. Haynes, B.W., Jr., Mafenide acetate in burn treatment. N Engl J Med, 1971. 284(23): p. 1324. [3]. Haik, J., et al., Burn care standards in Israel: lack of consensus. Burns, 2005. 31(7): p. 845-9.