化学性质
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 529.14 |
Cas No. | 367514-88-3 |
Formula | C28H37ClN4O2S |
Solubility | insoluble in H2O; insoluble in EtOH; ≥11.11 mg/mL in DMSO with gentle warming |
Chemical Name | (3aR,4R,7R,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione hydrochloride |
Canonical SMILES | Cl[H].O=C(C1([H])[C@](C([H])([H])C2([H])[H])([H])C([H])([H])C2([H])C13[H])N(C([H])([H])C4([H])C(C([H])([H])N5C([H])([H])C([H])([H])N(C6=NSC7=C6C([H])=C([H])C([H])=C7[H])C([H])([H])C5([H])[H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C3=O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
Lurasidone Hcl (SM 13496 Hcl) is an inhibitor of Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively, which is an atypical antipsychotic.