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Pratosartan(FW 7203)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pratosartan(FW 7203)图片
CAS NO:153804-05-8
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
Pratosartan (FW 7203) 是一种选择性血管紧张素 II 受体拮抗剂。
Cas No.153804-05-8
别名FW 7203; KD 3-671; KT 3671
Canonical SMILESO=C1CCCCC2=C1N(CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3)C(CCC)=N2
分子式C25H26N6O
分子量426.51
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Pratosartan is a selective angiotensin II receptor antagonist.

Pratosartan, which is an orally active angiotensin II (AII) antagonist, exhibiting selective and potent antagonistic activity to AT1 subtype[1]. Pratosartan is a new angiotensin II type 1 receptor blocker. Pratosartan is an effective and well tolerated antihypertensive drug, and may has beneficial effect on hypertensive patients with some metabolic disorders[2].

[1]. Sonegawa M, et al. Synthesis and pharmacological activity of the metabolites of Pratosartan. Chem Pharm Bull (Tokyo). 2006 Jun;54(6):782-7. [2]. Ogihara T, et al. Clinical efficacy of a new angiotensin II type 1 receptor blocker, pratosartan, in hypertensive patients. Hypertens Res. 2008 Feb;31(2):281-7.