化学性质
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 471.67 |
| Cas No. | 50679-08-8 |
| Formula | C32H41NO2 |
| Solubility | insoluble in H2O; ≥18 mg/mL in DMSO; ≥8.06 mg/mL in EtOH with ultrasonic |
| Chemical Name | 1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol |
| Canonical SMILES | CC(C)(C)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
资料参考
Terfenadine is a histamine H1-receptor antagonist, which blocks HERG and KATP (KIR6) channels. The IC values for Terfenadines inhibitory activity against these channels is 204nM for HERG and 1.2μM for KATP. Studies show that Terfenadine inhibits the delayed rectifier K+ in ventricular myocytes. Terfenadine is converted into its more active form, terfenadine carboxylate by the enzyme CYP3A4.
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