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Ziprasidone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ziprasidone图片
CAS NO:146939-27-7
包装:100mg
市场价:1000元

产品介绍

化学性质

Physical AppearanceA solid
StorageStore at -20°C
M.Wt412.94
Cas No.146939-27-7
FormulaC21H21ClN4OS
SynonymsGeodon;CP 88059;CP-88059;CP88059
Solubility≥20.65 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
Chemical Name5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one
Canonical SMILESC1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54
运输条件蓝冰运输或根据您的需求运输。
一般建议为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。

资料参考

Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects in preclinical assays predictive of antipsychotic activity. Whereas Ziprasidone is a dopamine antagonist in vitro and in vivo, its most potent action is antagonism of 5-HT2A receptors, where its affinity is an order of magnitude greater than that observed for dopamine D2 sites. Additionally, Ziprasidone inhibits neuronal uptake of 5-HT and norepinephrine comparable to the antidepressant imipramine. Ziprasidone differs from other atypical antipsychotic drugs in several clinically important ways, although further experience is necessary to clarify the significance of these differences.