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Carviolin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Carviolin图片
CAS NO:478-35-3
包装:1mg
市场价:4158元

产品介绍
Carviolin 是从新保加利亚 pura 子囊菌菌丝体中分离出来的化合物。
Cas No.478-35-3
Canonical SMILESO=C1C2=C(C=C(CO)C=C2OC)C(C3=CC(O)=CC(O)=C31)=O
分子式C16H12O6
分子量300.3
溶解度Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Carviolin is an anthraquinone fungal metabolite that has been found inZ. longicaudatawith immunosuppressive and antitrypanosomal activities.1,2It inhibits LPS- or concanavalin A-induced proliferation of mouse splenocytes (IC50s = 4 and 4.5 µg/ml, respectively).1Carviolin is active againstT. b. brucei(MIC = 41.66 µM).2

1.Fujimoto, H., Nakamura, E., Okuyama, E., et al.Six immunosuppressive features from an ascomycete, Zopfiella longicaudata, found in a screening study monitored by immunomodulatory activityChem. Pharm. Bull. (Tokyo)52(8)1005-1008(2004) 2.Aly, A.H., Debbab, A., Clements, C.M., et al.NF kappa B inhibitors and antitrypanosomal metabolites from endophytic fungus Penicillium sp. isolated from Limonium tubiflorumBioorg. Med. Chem.19(1)414-421(2011)