您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Effusol
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Effusol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Effusol图片
CAS NO:73166-28-6
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Effusol时可从Juncuseffuses中分离得到的一种酚类物质,对DPPH和ABTS自由基具有较强的清除活性,其IC50值分别为79μM和2.73μM。Effusol挽救皮质酮减弱的CA1LTP,保护海马功能对抗应激诱导的认知能力下降。
Cas No.73166-28-6
别名灯心草菲酚
Canonical SMILESOC(C(C)=C1CC2)=CC=C1C3=C2C=C(O)C=C3C=C
分子式C17H16O2
分子量252.31
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Effusol, a phenolic constituent from Juncus effuses, exhibits potent scavenging activity for DPPH and ABTS radicals, with IC50 values of 79 μM and 2.73 μM, respectively. Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampal function against stress-induced cognitive decline[1].

[1]. Kim, Ye Jin, et al. Antioxidant and Cytotoxic Activity of Compounds from the Stem of Juncus effuses. Journal of Applied Biological Chemistry. Volume 57 Issue 1 / Pages.47-51 / 2014 / 1976-0442(pISSN). [2]. Haruna Tamano, et al. CA1 LTP Attenuated by Corticosterone Is Canceled by Effusol via Rescuing Intracellular Zn 2+ Dysregulation. Cell Mol Neurobiol. 2019 Oct;39(7):975-983.